10 Warning Signs Your Kidneys May Be in Danger (Page 2 ) | March 22, 2025

2. Fatigue and Weakness

Kidneys help produce red blood cells by releasing a hormone called erythropoietin. When kidney function declines, anemia can develop, causing fatigue, weakness, and difficulty concentrating.

3. Swelling (Edema)

Fluid retention due to poor kidney function leads to swelling in the:

Legs
Hands
Face
Abdomen
4. Persistent Back Pain

Severe pain below the ribcage or tenderness in the back could be related to untreated urinary tract infections or kidney stones.

5. Unexplained Weight Loss or Loss of Appetite

Kidney disease can cause a loss of appetite and weight due to waste buildup in the blood. You may feel full even when you haven’t eaten much.

6. Nausea and Vomiting

Waste accumulation in the bloodstream often causes nausea or vomiting, especially in the morning or after meals.

7. Difficulty Sleeping

People with kidney disease frequently report trouble sleeping due to:

Nighttime muscle cramps
Restless leg syndrome
Frequent urination disrupting sleep
8. Metallic Taste in the Mouth

A persistent metallic taste is a common symptom of uremia, caused by the buildup of waste products in the blood.

9. Muscle Cramps and Twitching

Electrolyte imbalances, especially low calcium or high phosphorus levels, can result in painful cramps and muscle twitching.

10. Itchy Skin

The accumulation of toxins due to reduced kidney function can lead to intense, generalized itching.

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