Preheat your oven to 375°F (190°C). Lightly coat a 12-cup muffin tin with cooking spray.
In a large mixing bowl, combine the ground beef, breadcrumbs, Parmesan cheese, milk, ketchup, egg, onion, garlic powder, oregano, salt, and black pepper. Mix thoroughly using your hands or a spoon until the ingredients are well incorporated.
Evenly divide the meat mixture into the prepared muffin tin, gently pressing the mixture into each cup.
Brush the tops of each mini meatloaf muffin with an extra layer of ketchup for added flavor.
Bake for 20-25 minutes, or until the muffins are cooked through and golden brown on top.
Once baked, allow the mini meatloaf muffins to cool slightly before removing them from the tin. Use a knife or spatula to carefully lift them out.
Serve warm, accompanied by your favorite sides such as mashed potatoes, steamed vegetables, or a fresh salad.
Enjoy a delicious and easy-to-make meal with these savory mini meatloaf muffins!