Vitamin K Precursor Found to Target and Destroy Cancer Cells in Latest Research (Page 2 ) | May 15, 2025

Vitamin E Studies
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A trial conducted by the National Cancer Institute in 2001 attempted to establish whether an antioxidant vitamin E supplement could effectively cure or help prevent prostate cancer from developing. This trial was meant to last for 12 years and involved 35,000 men. However, the men were told to stop taking the vitamin E supplements only three years into the trial. This is because not only has the supplement not slowed down or prevented the development of prostate cancer, but actually resulted in more men getting the disease!

The New Study Involving Mice
lab mice
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After Professor Lloyd Trotman saw the results of the vitamin E study, he started to wonder if a pro-oxidant would work, seeing that an anti-oxidant had failed. His new study involving mice revealed that his hunch was indeed correct. When mice afflicted with prostate cancer received menadione, it disrupted the cancer’s survival processes. The researchers found that menadione destroyed prostate cancer cells by eliminating a lipid called PI(3)P.
Hopes That The Results Will Translate to Human Studies
microscope
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The team hopes to see the results replicated in pilot research in human patients with prostate cancer. According to Trotman, “Our target group would be men who get biopsies and have an early form of the disease diagnosed. We wonder if they start to take the supplement, whether we would be able to slow that disease down.” An unexpected benefit of menadione administration is that it has also been shown to be effective against myotubular myopathy. This rare condition inhibits muscle growth in baby boys. Those who are diagnosed with this disease rarely survive past their early childhood. The researchers discovered that using menadione to deplete the PI(3)P doubled the lifespan of mice suffering from myotubular myopathy.

The Bottom Line on Vitamin K and Prostate Cancer Prevention
man looking through microscope
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While studies with mice have proven successful, we are yet to see if these results translate to human subjects too. If so, it could change the lives of millions of men who are diagnosed with prostate cancer every year. This would mean a better quality of life for men who had previously had to suffer from this horrible condition. So far, this precursor to vitamin K is showing promising results and offering a brighter future for many.

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